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Overview
What Rembrandt depicted in this etching is not physically possible. With such a bright light in the window, this chamber could not possibly have remained so very dark. Clearly, Rembrandt knew this; then why did he do it? People love to tell stories about Rembrandt; the fact that this etching was made the same year as his wife Saskia died prematurely and the deaths of their three children shortly after childbirth, has been linked to his allegedly depressed mental condition.
This impression is a second state etching (the first two of the three were by Rembrandt himself). The window has been enlarged by burnishing and the outline of the right-hand curtain is now concave.
References: New Hollstein Dutch 212, 2nd of 3 states; Hollstein Dutch 105, 2nd of 2 states
See:
Masterworks Fine Art, https://www.masterworksfineart.com/artist/harmensz-van-rijn-rembrandt/st-jerome-in-a-dark-chamber-1642/
Joseph J. Schildkraut, 'Saint Jerome in a Dark Chamber: Rembrandt’s Metaphoric Portrayal of the Depressed Mind',
http://ajp.psychiatryonline.org/doi/pdf/10.1176/appi.ajp.161.1.26
Dr Mark Stocker Curator, Historical International Art September 2017